Nottingham Health Science Biobank

The Nottingham Health Science Biobank (NHSB) and related bioinformatics strategy is led by Dr Brian Thomson, Director the NHSB and Clinical lead for the 100K Genome project. This is a Trust led Biobank which is working closely with the Biomedical Research Units (BRUs), University of Nottingham and Nottingham NHS Treatment Centre on behalf of the wider scientific community. The aim is to provide a single, centralised, quality assured, biofluid and tissue resource to underpin translational studies in the Trust and University and to provide added value to clinical trials. Health research is one of the founding principles of the NHS; it is critical for improved quality of life and more effective healthcare delivery. The NHSB is a unique facility which will take advantage of Nottingham University Hospitals very large and diverse patient population, which is a key strength of Nottingham as a future centre for research excellence. Dr Brian Thomson and Dr Balwir Matharoo-Ball head a team based in the department of Pathology which consists of scientists, data analysts, a consent nurse and administration support sited at the City Hospital and Queen’s Medical Centre. The NHSB is able to offer high quality samples, collected under strictly controlled sampling conditions. Specific quality control data and basic demographics are available for each sample. The NHSB can also offer fully validated clinical data.

Services

  • Access to the full pathology archive
  • Data analytics
  • Digital imaging
  • Immunohistochemistry - scoring
  • Immunohistochemistry - staining
  • Tissue micro array creation
  • Nucleic acid extraction

Existing samples:

  • Hemochromatosis (disorder)
  • Malignant tumor of kidney (disorder)
  • Malignant tumor of prostate (disorder)
  • Malignant tumor of stomach (disorder)
  • Malignant tumor of testis (disorder)
  • Malignant tumor of urinary bladder (disorder)
  • Malignant tumour of breast
  • Malignant tumour of colon
  • Malignant tumour of lung
  • Malignant tumour of oesophagus
  • Malignant tumour of ovary
  • Malignant tumour of pancreas
  • Osteoarthritis
  • Rheumatoid arthritis
  • Secondary malignant neoplasm of colon (disorder)

Annual Statistics

Year Access Requests Received Access Requests Approved
Internal External Commercial Internal External Commercial
2015 N/A N/A N/A N/A N/A N/A
2016 N/A N/A N/A N/A N/A N/A
2017 N/A N/A N/A N/A N/A N/A
2018 N/A N/A N/A N/A N/A N/A