Fit and well (finding)

D0001 Swine Flu (Novel Influenza A H1N1) Vaccine Study

Year Started: 2009

Two new vaccines (Baxter swine flu & GSK swine flu vaccine) have been made against swine flu in response to the pandemic. These vaccines have been tested in adults, but there is less information on how well they work in children. This study will assess these two new vaccines in children aged between six months and twelve years



Access:
Access restricted at present
Type:
Clinical Trial
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 0 - 10%
Serum -60°C to -85°C N/A Not applicable 11 - 25%
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%

Tonsillitis (disorder)

D0004 Deposit of tonsils, adenoids and additional samples

Year Started: 2009

Children going for adenotonsillectomy, tonsillectomy or adenoidectomy will be approached to donate samples. Additional samples to be collected at this time may include saliva samples, urine samples, a blood sample and a nasal swab



Access:
Access restricted at present
Type:
Clinical Trial
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Saliva -60°C to -85°C N/A Not applicable 0 - 10%
Serum -60°C to -85°C N/A Not applicable 0 - 10%
Tissue specimen Surgical procedure (procedure) -60°C to -85°C N/A Not applicable 11 - 25%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Saliva -60°C to -85°C N/A Not applicable 0 - 10%
Serum -60°C to -85°C N/A Not applicable 0 - 10%
Tissue specimen Surgical procedure (procedure) -60°C to -85°C N/A Not applicable 0 - 10%

Chronic multifocal osteomyelitis (disorder)

D0005 Chronic Recurrent Multi focal Osteomyelitis

Year Started: 2013

Donors will be identified as satisfying the diagnostic criteria for Chronic Recurrent Multifocal Osteomyelitis through clinical consultations.



Access:
Access restricted at present
Type:
Disease specific
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
RNA -60°C to -85°C N/A Not applicable 11 - 25%
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%

Fit and well (finding)

D0008 Multi-centre Study to Evaluate the Safety, Tolerability and Immunogenicity of Baxter H1N1 vaccine and GlaxoSmithKline H1N1 vaccine in children 6 months to 12 years of age

Year Started: 2009

D0008 Multi-centre Study to Evaluate the Safety, Tolerability and Immunogenicity of Baxter H1N1 vaccine and GlaxoSmithKline H1N1 vaccine in children 6 months to 12 years of age



Access:
Access restricted at present
Type:
Clinical Trial
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 0 - 10%
Serum -60°C to -85°C N/A Not applicable 11 - 25%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 0 - 10%
Serum -60°C to -85°C N/A Not applicable 0 - 10%

Fit and well (finding)

D0009 Study to evaluate the induction of immune memory following infant vaccination with a glycol-conjugate Neisseria Meningitidis serogroup C Vaccine

Year Started: 2011

Please note, this collection consists of blood clots but it is listed as plasma. Study to evaluate the induction of immune memory following infant vaccination with a glycol-conjugate Neisseria Meningitidis serogroup C Vaccine and to assess the immune response to the concurrent infant routine immunisations administered in consistent versus alternating limbs.



Access:
Access restricted at present
Type:
Clinical Trial
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 0 - 10%


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Serum -60°C to -85°C N/A Not applicable 11 - 25%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 0 - 10%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Serum -60°C to -85°C N/A Not applicable 0 - 10%

Fit and well (finding)

D0010 Comparison study of two H1N1 influenza vaccines in children

Year Started: 2010

A multi-centre, open-label, clinical, phase 4 trial, following on from a head-to-head comparison study of two H1N1 influenza vaccines in children, to compare firstly, the persistence of antibody against the A/California/7/2009 (H1N1) virus and secondly the immunogenicity and reactogenicity of one dose of a non-adjuvanted trivalent seasonal influenza vaccine, in children who had received a two-dose immunisation regimen of Celvapan or Pandemrix.



Access:
Access restricted at present
Type:
Clinical Trial
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Serum -60°C to -85°C N/A Not applicable 26 - 50%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Serum -60°C to -85°C N/A Not applicable 11 - 25%

Fit and well (finding)

D0011 Swine Flu (Influenza A H1N1) Follow on Vaccine Study

Year Started: 2010

A multi-centre, open-label, clinical, phase 4 trial, following on from a head-to-head comparison study of two H1N1 influenza vaccines in children, to compare firstly, the persistence of antibody against the A/California/7/2009 (H1N1) virus and secondly the immunogenicity and reactogenicity of one dose of a non-adjuvanted trivalent seasonal influenza vaccine, in children who had received a two-dose immunisation regimen of Celvapan or Pandemrix.



Access:
Access restricted at present
Type:
Clinical Trial
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Serum -60°C to -85°C N/A Not applicable 11 - 25%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Serum -60°C to -85°C N/A Not applicable 26 - 50%

Fit and well (finding)

D0015 Improved diagnosis of meningococcal, pneumococcal and group A streptococcal infections

Year Started: 2005

Improved diagnosis of meningococcal, pneumococcal and group A streptococcal infections



Access:
Access restricted at present
Type:
Disease specific
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Saliva -60°C to -85°C N/A Not applicable 0 - 10%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Saliva -60°C to -85°C N/A Not applicable 0 - 10%


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Urine -60°C to -85°C N/A Not applicable 0 - 10%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Urine -60°C to -85°C N/A Not applicable 0 - 10%


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Swab -60°C to -85°C N/A Not applicable 0 - 10%

Fit and well (finding)

D0036 Human responses to candidate pneumococcal vaccines (“PATH longitudinal study”)

Year Started: 2008

Samples were collected as part of the “PATH longitudinal study” from a total of 60 healthy children aged 0-16 years when they were undergoing routine adenoidectomy or adenotonsillectomy surgery.



Access:
Access restricted at present
Type:
Disease specific
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Swab -60°C to -85°C N/A Not applicable 0 - 10%