Fit and well (finding)

D0001 Swine Flu (Novel Influenza A H1N1) Vaccine Study

Year Started: 2009

Two new vaccines (Baxter swine flu & GSK swine flu vaccine) have been made against swine flu in response to the pandemic. These vaccines have been tested in adults, but there is less information on how well they work in children. This study will assess these two new vaccines in children aged between six months and twelve years



Access:
Access restricted at present
Type:
Clinical Trial
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Male

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 0 - 10%
Serum -60°C to -85°C N/A Not applicable 11 - 25%
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%


Female

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 0 - 10%
Serum -60°C to -85°C N/A Not applicable 0 - 10%
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%

Fit and well (finding)

D0015 Improved diagnosis of meningococcal, pneumococcal and group A streptococcal infections

Year Started: 2005

Improved diagnosis of meningococcal, pneumococcal and group A streptococcal infections



Access:
Access restricted at present
Type:
Disease specific
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Saliva -60°C to -85°C N/A Not applicable 0 - 10%


Male

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Saliva -60°C to -85°C N/A Not applicable 0 - 10%


Female

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Urine -60°C to -85°C N/A Not applicable 0 - 10%


Female

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Urine -60°C to -85°C N/A Not applicable 0 - 10%


Male

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Urine -60°C to -85°C N/A Not applicable 0 - 10%


Female

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%


Male

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%


Male

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Swab -60°C to -85°C N/A Not applicable 0 - 10%

Fit and well (finding)

D0016 Server, unusual, or recurrent community acquired infection in children- susceptibility, detection and immune response (CAI)

Year Started: 2006

What makes the bug choose your child, how can we find it and how can we stop it? The study is trying to improve our understanding of why some children get sick when others don’t, even though they must have been exposed to the same bugs. We are also trying to develop ways of finding out what has caused an infection, using ways which don’t rely on finding the bug itself (one example of this would be to test urine for evidence of the bug for example). The other part of the study is to use the information we can get from children who are infected by these bugs to help develop vaccines to increase our ability to prevent infections in the first place.



Access:
Access restricted at present
Type:
Disease specific
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%


Male

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Whole blood -60°C to -85°C N/A Not applicable 0 - 10%

Fit and well (finding)

D0026 Study to evaluate V419 (PR5I) given at 2, 3 & 4 months with two types of meningococcal serogroup C conjugate (MCC) vaccines given at 3 & 4 months, followed by a combined Haemophilus influenza type b-MCC vaccine at 12 months

Year Started: 2012

Please note, this collection consists of blood clots but it is listed as plasma. A phase III open-label randomised study, to evaluate the immunogenicity and safety of the concomitant administration of V419 (PR5I) given at 2, 3 and 4 months of age with two types of meningococcal serogroup C conjugate (MCC) vaccines given at 3 an 4 months of age, and followed by the administration at 12 months of age of a combined Haemophilus influenza type b-MCC vaccine.



Access:
Access restricted at present
Type:
Clinical Trial
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Male

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Plasma -60°C to -85°C N/A Not applicable 51 - 75%


Female

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Plasma -60°C to -85°C N/A Not applicable 26 - 50%

Fit and well (finding)

D0032 The Bristol Nasal Colonisation Surveillance Study

Year Started: 2011

The effects of viral upper respiratory tract infections on bacterial colonisation of the nasopharynx in young healthy children attending day care centres. A single centre prospective longitudinal follow up study.



Access:
Access restricted at present
Type:
Clinical Trial
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
There is no associated data for this collection.


Female

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Swab -60°C to -85°C N/A Not applicable 0 - 10%


Male

Infant (1 month - 2 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Swab -60°C to -85°C N/A Not applicable 0 - 10%