Carcinoma in situ of breast (disorder)

IBIS 3 (Feasibility)

Year Started: 2016

An International Breast Intervention Study investigating Prevention Of Late Recurrence in ER+ breast cancer survivors following 5 years of adjuvant treatment



Access:
Access restricted at present
Type:
Clinical Trial
Status:
In progress
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
Freezer temperature logs Immediate


Female

Adult (> 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Serum -60°C to -85°C N/A Affected 0 - 10%
Whole blood -60°C to -85°C N/A Affected 0 - 10%

Carcinoma in situ of breast (disorder)

IBIS-II

Year Started: 2002

IBIS-II (Prevention) trial was designed to continue the work started in IBIS-I in determining whether a chemopreventive strategy towards breast cancer is beneficial. IBIS-I was set up to investigate the use of tamoxifen as a preventive agent for women with moderate to increased risk of getting breast cancer. IBIS-II (Prevention) was a randomised double blind control trial but this time will compare anastrozole vs placebo. A companion study compared anastrozole to tamoxifen for women with locally excised ER or PgR +ve DCIS.



Access:
Open only through collaboration
Type:
Clinical Trial
Status:
In progress
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
Freezer temperature logs Immediate
Imaging data 0 - 3 months
Pathology records 0 - 3 months


Female

Adult (> 40 years)

5001 - 10000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Affected 75% -99%
Serum -60°C to -85°C N/A Affected 75% -99%
Tissue specimen Surgical procedure (procedure) RT Paraffin Non-affected 51 - 75%
Urine -60°C to -85°C N/A Affected 11 - 25%

Benign neoplasm of prostate (disorder)

PROVENT (Feasibility)

Year Started: 2016

A randomised, double blind, placebo controlled feasibility study to examine the clinical effectiveness of aspirin and/or Vitamin D3 to prevent disease progression in men on Active Surveillance for prostate cancer



Access:
Access restricted at present
Type:
Clinical Trial
Status:
In progress
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
Biomarker datasets > 6 months
Freezer temperature logs Immediate
Genomic datasets > 6 months


Male

Adult (> 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Serum -60°C to -85°C N/A Affected 0 - 10%
Tissue specimen Surgical procedure (procedure) RT Paraffin Non-affected 0 - 10%
Urine -60°C to -85°C N/A Non-affected 0 - 10%
Whole blood -60°C to -85°C N/A Affected 0 - 10%