Carcinoma in situ of breast (disorder)
IBIS-II
Year Started: 2002
IBIS-II (Prevention) trial was designed to continue the work started in IBIS-I in determining whether a chemopreventive strategy towards breast cancer is beneficial. IBIS-I was set up to investigate the use of tamoxifen as a preventive agent for women with moderate to increased risk of getting breast cancer. IBIS-II (Prevention) was a randomised double blind control trial but this time will compare anastrozole vs placebo. A companion study compared anastrozole to tamoxifen for women with locally excised ER or PgR +ve DCIS.
- Access:
- Open only through collaboration
- Type:
- Clinical Trial
- Status:
- In progress
- Consent restrictions:
- No restrictions
Associated Data Type | Procurement Timeframe |
---|---|
Freezer temperature logs | Immediate |
Imaging data | 0 - 3 months |
Pathology records | 0 - 3 months |
Female
Adult (> 40 years)
5001 - 10000 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
DNA | -60°C to -85°C | N/A | Affected | 75% -99% | |
Serum | -60°C to -85°C | N/A | Affected | 75% -99% | |
Tissue specimen | Surgical procedure (procedure) | RT | Paraffin | Non-affected | 51 - 75% |
Urine | -60°C to -85°C | N/A | Affected | 11 - 25% |
Benign neoplasm of prostate (disorder)
PROVENT (Feasibility)
Year Started: 2016
A randomised, double blind, placebo controlled feasibility study to examine the clinical effectiveness of aspirin and/or Vitamin D3 to prevent disease progression in men on Active Surveillance for prostate cancer
- Access:
- Access restricted at present
- Type:
- Clinical Trial
- Status:
- In progress
- Consent restrictions:
- No restrictions
Associated Data Type | Procurement Timeframe |
---|---|
Biomarker datasets | > 6 months |
Freezer temperature logs | Immediate |
Genomic datasets | > 6 months |
Male
Adult (> 40 years)
101 - 500 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Serum | -60°C to -85°C | N/A | Affected | 0 - 10% | |
Tissue specimen | Surgical procedure (procedure) | RT | Paraffin | Non-affected | 0 - 10% |
Urine | -60°C to -85°C | N/A | Non-affected | 0 - 10% | |
Whole blood | -60°C to -85°C | N/A | Affected | 0 - 10% |
Carcinoma in situ of breast (disorder)
IBIS I
Year Started: 1992
International Breast Cancer Intervention Study (IBIS-I) – a multicentre UKCCCR trial to evaluate the prevention of breast cancer in high risk women.
- Access:
- Open to applicants
- Type:
- Clinical Trial
- Status:
- Completed
- Consent restrictions:
- No restrictions
Associated Data Type | Procurement Timeframe |
---|---|
There is no associated data for this collection. |
Female
Adult (> 40 years)
101 - 500 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Tissue specimen | Surgical procedure (procedure) | RT | Paraffin | Non-affected | 75% -99% |
Whole blood | -60°C to -85°C | N/A | Affected | 75% -99% |