Diabetes mellitus type 1

Exeter Archival Diabetes Biobank (EADB)

Year Started: 1980

During his career as a pathologist working in Scotland, Professor Alan Foulis compiled the world’s largest collection of autopsy pancreas samples recovered from patients who died shortly after receiving a diagnosis of type 1 diabetes. This collection was first assembled in the early 1980s from centres across the UK and it consists of nearly 170 cases in total, more than 100 of which are from young people (<20 years old) with recent-onset type 1 diabetes. The samples were originally held in Glasgow but, upon his retirement in 2015, Professor Foulis transferred them to University of Exeter Medical School, where they are now retained. Study of these cases has been hugely influential in shaping our current understanding of the aetiology of type 1 diabetes. Although it is now more than 30 years since this collection was first compiled by Alan Foulis, it continues to represent an invaluable resource for research into the causes of type 1 diabetes and is likely to do so for many years to come.

Access:
Open only through collaboration
Type:
Disease specific
Status:
Completed
Collection point:
Multiple points in patient pathway
Consent restrictions:
No restrictions


Female

Adolescent (12 - 18 years)

11 - 100 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected


Male

Young adult (18 - 40 years)

11 - 100 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected


Female

Young adult (18 - 40 years)

11 - 100 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected


Female

Infant (1 month - 2 years)

1 - 10 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected


Female

Child (6 - 12 years)

11 - 100 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected


Male

Young child (2 - 6 years)

11 - 100 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected


Male

Adolescent (12 - 18 years)

11 - 100 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected


Female

Adult (> 40 years)

1 - 10 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected


Female

Young child (2 - 6 years)

11 - 100 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected


Male

Child (6 - 12 years)

11 - 100 donors

Material Type Preservation Type % of Sample Set Macroscopic Assessment
PM tissue Room temperature 100% Affected