Fit and well (finding)
Exeter Ten Thousand (EXTEND)
Year Started: 2009
The Exeter Ten Thousand study was started in 2009 to collect genetic, biological, clinical and lifestyle information on 10,000 adult individuals in the Exeter region in order to establish a sampling framework from which participants can be selected on the basis of genotypic or phenotypic predisposition / protection factors. Samples are selected for further analysis or individuals can be recontacted for recruitment. Participants who join Exeter 10000 are living in a community setting and are usually ambulant and well but may have diagnosed with clinical conditions Access to samples or data must be requested through the Steering Committee, which meets once a month.
- Access:
- Open only through collaboration
- Type:
- Cross-sectional
- Status:
- In progress
- Consent restrictions:
- Other animal work restriction, Xenograft restriction
| Associated Data Type | Procurement Timeframe |
|---|---|
| Biomarker datasets | 0 - 3 months |
| Clinical records | 0 - 3 months |
| Cold ischemic time | 0 - 3 months |
| Followup records | 0 - 3 months |
| Freezer temperature logs | 0 - 3 months |
| Genomic datasets | 0 - 3 months |
| Physiological/biochemical measurements | 0 - 3 months |
| Primary care records | 0 - 3 months |
| Quality indicators | 0 - 3 months |
Male
Young adult (18 - 40 years)
501 - 1000 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| DNA | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Plasma | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Serum | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Urine | -60°C to -85°C | N/A | Not applicable | 75% -99% |
Female
Young adult (18 - 40 years)
1001 - 3000 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| DNA | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Plasma | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Serum | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Urine | -60°C to -85°C | N/A | Not applicable | 75% -99% |
Male
Adult (> 40 years)
3001 - 5000 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| DNA | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Plasma | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Serum | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Urine | -60°C to -85°C | N/A | Not applicable | 75% -99% |
Female
Adult (> 40 years)
3001 - 5000 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| DNA | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Plasma | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Serum | -60°C to -85°C | N/A | Not applicable | 75% -99% | |
| Urine | -60°C to -85°C | N/A | Not applicable | 75% -99% |