Fit and well (finding)

Exeter Ten Thousand (EXTEND)

Year Started: 2009

The Exeter Ten Thousand study was started in 2009 to collect genetic, biological, clinical and lifestyle information on 10,000 adult individuals in the Exeter region in order to establish a sampling framework from which participants can be selected on the basis of genotypic or phenotypic predisposition / protection factors. Samples are selected for further analysis or individuals can be recontacted for recruitment. Participants who join Exeter 10000 are living in a community setting and are usually ambulant and well but may have diagnosed with clinical conditions Access to samples or data must be requested through the Steering Committee, which meets once a month.



Access:
Open only through collaboration
Type:
Cross-sectional
Status:
In progress
Consent restrictions:
Other animal work restriction, Xenograft restriction


Associated Data Type Procurement Timeframe
Biomarker datasets 0 - 3 months
Clinical records 0 - 3 months
Cold ischemic time 0 - 3 months
Followup records 0 - 3 months
Freezer temperature logs 0 - 3 months
Genomic datasets 0 - 3 months
Physiological/biochemical measurements 0 - 3 months
Primary care records 0 - 3 months
Quality indicators 0 - 3 months


Male

Adult (> 40 years)

3001 - 5000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 75% -99%
Plasma -60°C to -85°C N/A Not applicable 75% -99%
Serum -60°C to -85°C N/A Not applicable 75% -99%
Urine -60°C to -85°C N/A Not applicable 75% -99%


Female

Adult (> 40 years)

3001 - 5000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 75% -99%
Plasma -60°C to -85°C N/A Not applicable 75% -99%
Serum -60°C to -85°C N/A Not applicable 75% -99%
Urine -60°C to -85°C N/A Not applicable 75% -99%

Diabetes mellitus type 2 (disorder)

Diabetes Alliance for Research in England (DARE)

Year Started: 2009

The DARE study consists of samples from diabetic patients, both type 1 and type 2 in the South West peninsula area (roughly Devon and Cornwall), predominately within the Exeter area. Sample collected at point of contact and data collected over time. The DARE collection was run alongside our EXTEND collection, concentrating on diabetic patients. EXTEND patients were recruited as controls to the DARE collection, and DARE diabetics were recruited to the EXTEND collection. Therefore, the majority of patients in DARE will have samples held within EXTEND, however, if diabetes is the main focus of a request to the Exeter biobanks, samples and data will come from the DARE collection. Please see http://www.diabetesgenes.org/content/diabetes-alliance-research-england-dare-previously-known-exeter-research-alliance-extra-stud for more information



Access:
Open only through collaboration
Type:
Disease specific
Status:
Completed
Consent restrictions:
Other animal work restriction, Xenograft restriction


Associated Data Type Procurement Timeframe
Biomarker datasets 0 - 3 months
Clinical records 0 - 3 months
Cold ischemic time 0 - 3 months
Followup records 0 - 3 months
Freezer temperature logs 0 - 3 months
Genomic datasets 0 - 3 months
Physiological/biochemical measurements 0 - 3 months
Primary care records 0 - 3 months
Quality indicators 0 - 3 months


Male

Adult (> 40 years)

3001 - 5000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C N/A Not applicable 75% -99%
Plasma -60°C to -85°C N/A Not applicable 26 - 50%
Serum -60°C to -85°C N/A Not applicable 26 - 50%
Urine -60°C to -85°C N/A Not applicable 26 - 50%