Malignant tumor of rectum (disorder)
ARISTOTLE Trial: Blood Samples
Year Started: 2015
Whole blood samples will processed to collect:
(i) plasma samples at 4 timpoints for circulating tumour DNA (ctDNA): pre-treatment, during weeks 1 and 5 of treatment and during week 10 (after CRT)
(ii) buffy coat for germline DNA at any timepoint after recruitment
- Access:
- Access restricted at present
- Type:
- Disease specific
- Status:
- In progress
- Consent restrictions:
-
No restrictions
Associated Data Type |
Procurement Timeframe |
There is no associated data for this collection. |
Male
Young adult (18 - 40 years)
11 - 100 donors
Material Type |
Extraction Procedure |
Storage Temperature |
Preservation Type |
Macroscopic Assessment |
% of Sample Set |
Peripheral blood mononuclear cells (PBMC) |
|
-60°C to -85°C |
N/A |
Not applicable |
75% -99% |
Plasma |
|
-60°C to -85°C |
N/A |
Not applicable |
51 - 75% |
Male
Adult (> 40 years)
11 - 100 donors
Material Type |
Extraction Procedure |
Storage Temperature |
Preservation Type |
Macroscopic Assessment |
% of Sample Set |
Peripheral blood mononuclear cells (PBMC) |
|
-60°C to -85°C |
N/A |
Not applicable |
75% -99% |
Plasma |
|
-60°C to -85°C |
N/A |
Not applicable |
51 - 75% |
Female
Young adult (18 - 40 years)
11 - 100 donors
Material Type |
Extraction Procedure |
Storage Temperature |
Preservation Type |
Macroscopic Assessment |
% of Sample Set |
Peripheral blood mononuclear cells (PBMC) |
|
-60°C to -85°C |
N/A |
Not applicable |
75% -99% |
Plasma |
|
-60°C to -85°C |
N/A |
Not applicable |
51 - 75% |
Female
Adult (> 40 years)
11 - 100 donors
Material Type |
Extraction Procedure |
Storage Temperature |
Preservation Type |
Macroscopic Assessment |
% of Sample Set |
Peripheral blood mononuclear cells (PBMC) |
|
-60°C to -85°C |
N/A |
Not applicable |
75% -99% |
Plasma |
|
-60°C to -85°C |
N/A |
Not applicable |
51 - 75% |