Malignant tumor of biliary tract (disorder)
ABC-07- Addition of stereotactic body radiotherapy to systemic chemotherapy in locally advanced biliary tract cancers
Year Started: 2015
• Archival paraffin-embedded tissue - a representative archival block of the tumour tissue from a biopsy or prior surgery. • Whole blood for ctDNA - will be collected at 4 time points, Pre-treatment, end of cycle 4, completion of treatment and at 6 month follow up or at disease progression. • Whole blood for germline DNA- will be collected from patients pre-treatment (within 14 days prior to starting CisGem). • Serum samples (optional for trial sites)- will be collected a 4 different time points, Pre-treatment, end of cycle 4, completion of treatment and at 6 month follow up or at disease progression.
- Access:
- Closed to access
- Type:
- Disease specific
- Status:
- In progress
- Consent restrictions:
- No restrictions
| Associated Data Type | Procurement Timeframe |
|---|---|
| Clinical records | 3 - 6 months |
| Followup records | 3 - 6 months |
| Freezer temperature logs | > 6 months |
| Imaging data | 3 - 6 months |
| Treatment records | 3 - 6 months |
Male
Adult (> 40 years)
11 - 100 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| Tissue specimen | RT | Not applicable | 51 - 75% | ||
| Serum | -60°C to -85°C | Not applicable | 51 - 75% | ||
| Plasma | -60°C to -85°C | Not applicable | 51 - 75% | ||
| Whole blood | -60°C to -85°C | Not applicable | 51 - 75% |
Female
Adult (> 40 years)
11 - 100 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| Serum | -60°C to -85°C | Not applicable | 51 - 75% | ||
| Tissue specimen | RT | Paraffin | Not applicable | 51 - 75% | |
| Plasma | -60°C to -85°C | Not applicable | 51 - 75% | ||
| Whole blood | -60°C to -85°C | Not applicable | 51 - 75% |