Malignant tumor of biliary tract (disorder)
ABC-07- Addition of stereotactic body radiotherapy to systemic chemotherapy in locally advanced biliary tract cancers
Year Started: 2015
• Archival paraffin-embedded tissue - a representative archival block of the tumour tissue from a biopsy or prior surgery. • Whole blood for ctDNA - will be collected at 4 time points, Pre-treatment, end of cycle 4, completion of treatment and at 6 month follow up or at disease progression. • Whole blood for germline DNA- will be collected from patients pre-treatment (within 14 days prior to starting CisGem). • Serum samples (optional for trial sites)- will be collected a 4 different time points, Pre-treatment, end of cycle 4, completion of treatment and at 6 month follow up or at disease progression.
- Access:
- Closed to access
- Type:
- Disease specific
- Status:
- In progress
- Consent restrictions:
- No restrictions
Associated Data Type | Procurement Timeframe |
---|---|
Clinical records | 3 - 6 months |
Followup records | 3 - 6 months |
Freezer temperature logs | > 6 months |
Imaging data | 3 - 6 months |
Treatment records | 3 - 6 months |
Male
Adult (> 40 years)
11 - 100 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Tissue specimen | RT | Not applicable | 51 - 75% | ||
Serum | -60°C to -85°C | Not applicable | 51 - 75% | ||
Plasma | -60°C to -85°C | Not applicable | 51 - 75% | ||
Whole blood | -60°C to -85°C | Not applicable | 51 - 75% |
Male
Young adult (18 - 40 years)
1 - 10 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Whole blood | -60°C to -85°C | Not applicable | 51 - 75% | ||
Tissue specimen | RT | Paraffin | Not applicable | 51 - 75% | |
Plasma | -60°C to -85°C | Not applicable | 51 - 75% | ||
Serum | -60°C to -85°C | Not applicable | 51 - 75% |
Female
Adult (> 40 years)
11 - 100 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Serum | -60°C to -85°C | Not applicable | 51 - 75% | ||
Tissue specimen | RT | Paraffin | Not applicable | 51 - 75% | |
Plasma | -60°C to -85°C | Not applicable | 51 - 75% | ||
Whole blood | -60°C to -85°C | Not applicable | 51 - 75% |