Systemic lupus erythematosus (disorder)
BHSLE: Sequencing Based Genetic Analysis of Systemic Lupus Erythematosus (SLE)
Year Started: 2015
DNA and clinical information are used to look for similarities and differences between people with SLE and those unaffected by the disease. These data can be used to identify genetic differences that are more common in SLE patients and then ask how these genetic factors affect the immune system and how they influence the nature and severity of the disease. Current recruitment status for this study is 220 patients.
- Access:
- Closed to access
- Type:
- Disease specific
- Status:
- In progress
- Consent restrictions:
- Xenograft restriction
| Associated Data Type | Procurement Timeframe |
|---|---|
| Clinical records | 3 - 6 months |
| Freezer temperature logs | 0 - 3 months |
| Donor Ethnicity | 3 - 6 months |
Unknown
Data not recorded
101 - 500 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| DNA | -60°C to -85°C | N/A | Affected | 75% -99% | |
| Peripheral blood mononuclear cells (PBMC) | Liquid nitrogen liquid phase | N/A | Affected | 51 - 75% | |
| Plasma | -60°C to -85°C | N/A | Affected | 75% -99% |