Psoriatic arthritis (disorder)
PEAC: Pathobiology of Early Arthritis Cohort
Year Started: 2008
Prospective, observational study in patients with early symptomatic inflammatory arthritis (http://www.peac-mrc.mds.qmul.ac.uk/). Biological samples (synovial tissue & fluids) are collected at two timepoints - Baseline & Follow-up (6 month), please note figures for baseline samples are represented (6 month sample availability on request). Demographic & clinical data is available & collected at 5 timepoints over a 1-year follow-up period (Baseline, 3, 6, 9 & 12 months). Current recruitment status for Psoriatic Arthritis cohort is 44 patients (1st April 2019).
- Access:
- Closed to access
- Type:
- Cohort
- Status:
- In progress
- Consent restrictions:
- Xenograft restriction
| Associated Data Type | Procurement Timeframe |
|---|---|
| Biomarker datasets | 0 - 3 months |
| Clinical records | 0 - 3 months |
| Followup records | 0 - 3 months |
| Freezer temperature logs | 0 - 3 months |
| Genomic datasets | 0 - 3 months |
| Imaging data | 0 - 3 months |
| Pathology records | 0 - 3 months |
| Physiological/biochemical measurements | 0 - 3 months |
| Quality indicators | 0 - 3 months |
| Treatment records | 0 - 3 months |
| Donor Ethnicity | 0 - 3 months |
Unknown
Data not recorded
11 - 100 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| Peripheral blood mononuclear cells (PBMC) | Liquid nitrogen liquid phase | N/A | Affected | 75% -99% | |
| Plasma | -60°C to -85°C | N/A | Affected | 75% -99% | |
| RNA | -60°C to -85°C | N/A | Affected | 51 - 75% | |
| Serum | -60°C to -85°C | N/A | Affected | 75% -99% | |
| Tissue specimen | Surgical procedure (procedure) | RT | Paraffin | Affected | 75% -99% |
| Urine | -60°C to -85°C | N/A | Affected | 75% -99% |
Undifferentiated inflammatory arthritis (disorder)
PEAC: Pathobiology of Early Arthritis Cohort
Year Started: 2008
Prospective, observational study in patients with early symptomatic inflammatory arthritis (http://www.peac-mrc.mds.qmul.ac.uk/). Biological samples (synovial tissue & fluids) are collected at two timepoints - Baseline & Follow-up (6 month), please note figures for baseline samples are represented (6 month sample availability on request). Demographic & clinical data is available & collected at 5 timepoints over a 1-year follow-up period (Baseline, 3, 6, 9 & 12 months). Current recruitment status for the Undifferentiated/Non-Inflammatory Arthritis cohort is 65 patients (1st April 2019).
- Access:
- Closed to access
- Type:
- Cohort
- Status:
- In progress
- Consent restrictions:
- Xenograft restriction
| Associated Data Type | Procurement Timeframe |
|---|---|
| Biomarker datasets | 0 - 3 months |
| Clinical records | 0 - 3 months |
| Followup records | 0 - 3 months |
| Freezer temperature logs | 0 - 3 months |
| Genomic datasets | 0 - 3 months |
| Imaging data | 0 - 3 months |
| Pathology records | 0 - 3 months |
| Quality indicators | 0 - 3 months |
| Treatment records | 0 - 3 months |
| Donor Ethnicity | 0 - 3 months |
Unknown
Data not recorded
11 - 100 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| Peripheral blood mononuclear cells (PBMC) | Liquid nitrogen liquid phase | N/A | Affected | 75% -99% | |
| Plasma | -60°C to -85°C | N/A | Affected | 75% -99% | |
| RNA | -60°C to -85°C | N/A | Affected | 51 - 75% | |
| Serum | -60°C to -85°C | N/A | Affected | 75% -99% | |
| Tissue specimen | Surgical procedure (procedure) | RT | Paraffin | Affected | 75% -99% |
| Urine | -60°C to -85°C | N/A | Affected | 75% -99% |
Rheumatoid arthritis (disorder)
THERAPIST: TH17 Responses Evaluated in RA Patients on Inhibitors of TNFα
Year Started: 2015
Observational, prospective study, multi-centre (http://www.trp-nocri.whri.qmul.ac.uk/). Biological samples (synovial tissue & fluids) collected at multiple timepoints (details available on request), please note figures for baseline samples are represented (availability of samples from other timepoints on request). Tissue available only for patients recruited to the sub-study arm (details available on request). Demographic & clinical data is available & collected at multiple timepoints over a 6 month follow-up period. Recruitment status for this study is 56 patients.
- Access:
- Closed to access
- Type:
- Cohort
- Status:
- Completed
- Consent restrictions:
- Xenograft restriction
| Associated Data Type | Procurement Timeframe |
|---|---|
| Biomarker datasets | 0 - 3 months |
| Clinical records | 0 - 3 months |
| Followup records | 0 - 3 months |
| Freezer temperature logs | 0 - 3 months |
| Imaging data | 0 - 3 months |
| Pathology records | 0 - 3 months |
| Physiological/biochemical measurements | 0 - 3 months |
| Quality indicators | 0 - 3 months |
| Treatment records | 0 - 3 months |
| Donor Ethnicity | 0 - 3 months |
Unknown
Data not recorded
11 - 100 donors
| Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
|---|---|---|---|---|---|
| Peripheral blood mononuclear cells (PBMC) | Liquid nitrogen liquid phase | N/A | Affected | 75% -99% | |
| RNA | -60°C to -85°C | N/A | Affected | 26 - 50% | |
| Serum | -60°C to -85°C | N/A | Affected | 75% -99% | |
| Tissue specimen | Surgical procedure (procedure) | RT | Paraffin | Affected | 26 - 50% |
| Urine | -60°C to -85°C | N/A | Affected | 75% -99% | |
| Whole blood | -60°C to -85°C | N/A | Affected | 75% -99% |