Rheumatoid arthritis (disorder)
THERAPIST: TH17 Responses Evaluated in RA Patients on Inhibitors of TNFα
Year Started: 2015
Observational, prospective study, multi-centre (http://www.trp-nocri.whri.qmul.ac.uk/). Biological samples (synovial tissue & fluids) collected at multiple timepoints (details available on request), please note figures for baseline samples are represented (availability of samples from other timepoints on request). Tissue available only for patients recruited to the sub-study arm (details available on request). Demographic & clinical data is available & collected at multiple timepoints over a 6 month follow-up period. Recruitment status for this study is 56 patients.
- Access:
- Closed to access
- Type:
- Cohort
- Status:
- Completed
- Consent restrictions:
- Xenograft restriction
Associated Data Type | Procurement Timeframe |
---|---|
Biomarker datasets | 0 - 3 months |
Clinical records | 0 - 3 months |
Followup records | 0 - 3 months |
Freezer temperature logs | 0 - 3 months |
Imaging data | 0 - 3 months |
Pathology records | 0 - 3 months |
Physiological/biochemical measurements | 0 - 3 months |
Quality indicators | 0 - 3 months |
Treatment records | 0 - 3 months |
Donor Ethnicity | 0 - 3 months |
Unknown
Data not recorded
11 - 100 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Peripheral blood mononuclear cells (PBMC) | Liquid nitrogen liquid phase | N/A | Affected | 75% -99% | |
RNA | -60°C to -85°C | N/A | Affected | 26 - 50% | |
Serum | -60°C to -85°C | N/A | Affected | 75% -99% | |
Tissue specimen | Surgical procedure (procedure) | RT | Paraffin | Affected | 26 - 50% |
Urine | -60°C to -85°C | N/A | Affected | 75% -99% | |
Whole blood | -60°C to -85°C | N/A | Affected | 75% -99% |