The Covid-19 collection consists of blood, serum, saliva, sputum, nasal strips, nasopharyngeal & oropharyngeal swabs and pleural fluid from patients infected with the novel coronavirus. In some cases, longitudinal samples have and will be collected, which could include samples prior to or after infections with Covid-19. The Covid-19 collection aims to promote biomedical research by providing biomaterial to academic and commercial researchers/partners to facilitate high-quality research to answer a range of questions including: • How does Covid-19 make some people severely unwell? • Does our immune system protect us from re-infection with COVID-19 after we have recovered from infection? • How well do tests for Covid-19 work? • What are the best ways to identify or test for Covid-19? • How does the body respond throughout the course of infection, recovery and possible reinfection? • How long does our immune system protects us from re-infection with Covid-19 after we have recovered from infection? • How does the immune system contribute to long-term post viral symptoms? The biological samples collected will enable a number of different analyses to be performed. This may include (but is not limited to): • The effects of long Covid-19 • Biomarker studies • Immunological studies • Multi-morbidity studies • Functional analysis of cells of the respiratory system

The respiratory collection has approximately 500 samples with associated clinical data. The collection includes samples of whole blood taken from adults who have respiratory or respiratory related conditions, but also includes other biological samples (plasma, sputum, broncho-alveolar lavage, pleural fluid, solid tissue). The respiratory collection aims to promote biomedical research by providing biomaterial to academic and commercial researchers/partners to facilitate high-quality research to improve the diagnosis and treatment of respiratory diseases, that is lung disease, including (but not limited to) inflammatory, obstructive and restrictive lung disorders, respiratory tract infections, pleural cavity disease, malignancies relating to the respiratory system and pulmonary vascular conditions. The biological samples collected will enable a number of different analyses to be performed. This may include (but is not limited to): • Gene expression analysis • Biomarker discovery • Immunological studies • Multi-morbidity studies • Functional analysis of cells of the respiratory system

The respiratory collection has approximately 500 samples with associated clinical data. The collection includes samples of whole blood taken from adults who have respiratory or respiratory related conditions, but also includes other biological samples (plasma, sputum, broncho-alveolar lavage, pleural fluid, solid tissue). The respiratory collection aims to promote biomedical research by providing biomaterial to academic and commercial researchers/partners to facilitate high-quality research to improve the diagnosis and treatment of respiratory diseases, that is lung disease, including (but not limited to) inflammatory, obstructive and restrictive lung disorders, respiratory tract infections, pleural cavity disease, malignancies relating to the respiratory system and pulmonary vascular conditions. The biological samples collected will enable a number of different analyses to be performed. This may include (but is not limited to): • Gene expression analysis • Biomarker discovery • Immunological studies • Multi-morbidity studies • Functional analysis of cells of the respiratory system