Chronic kidney disease (disorder)

MRC/Kidney Research UK National DNA Bank for Glomerulonephritis

Year Started: 2001

The glomerulonephritis sample collection consists of DNA samples from Caucasian participants recruited from renal units throughout the UK with one of five glomerular diseases – IgA nephropathy, membranous nephropathy, vasculitis, lupus nephritis and minimal change disease. Trios with Iga nephropathy, control samples and samples from relatives were also collected. Participants were aged 18 years or above. Collection commenced: April 2001 (completed December 2006) IgA Nephropathy (536 cases, 203 controls unrelated, 591 relatives, 222 trios) Membranous Nephropathy (359 cases, 155 controls unrelated, 4 relatives) Vasculitis (457 cases, 219 controls unrelated, 5 relatives) Lupus nephritis (236 cases, 71 controls unrelated, 106 relatives) Minimal Change Disease (153 cases, 59 controls unrelated, 122 relatives, 34 trios)



Access:
Open to applicants
Type:
Disease specific
Status:
Completed
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
Clinical records > 6 months
Freezer temperature logs 0 - 3 months
Genomic datasets 0 - 3 months
Pathology records > 6 months
Physiological/biochemical measurements > 6 months
Quality indicators 0 - 3 months
Treatment records > 6 months
Donor Ethnicity > 6 months


Male

Adult (> 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C Not applicable 100%


Male

Young adult (18 - 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C Not applicable 100%


Female

Young adult (18 - 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C Not applicable 100%


Female

Adult (> 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -60°C to -85°C Not applicable 100%