Local recurrence of malignant tumor of rectum (disorder)
ELECTRA
Year Started: 2022
ELECTRA is a feasibility trial to determine whether it is acceptable and feasible to recruit, randomise and deliver Intraoperative Electron Radiotherapy (IOERT) in a randomised controlled trial setting. Patients with locally advanced rectal cancer or locally recurrent rectal cancer involving the pelvic sidewall or posterior bony pelvis will be randomised to receive either extended margin surgery along, extended margin surgery with IOERT at standard dose (10 Gy), or extended margin surgery with IOERT at higher dose (15 Gy). Patients will be randomised to the three treatment arms in a 1:1:1 ratio. Patients will be followed up for a minimum of 12 months and up to 24 months following their surgery.
- Access:
- Data access only
- Type:
- Clinical Trial
- Status:
- Not-started
- Consent restrictions:
- Commercial restriction, DNA restriction, Other animal work restriction, Xenograft restriction
Associated Data Type | Procurement Timeframe |
---|---|
Clinical records | > 6 months |
Male
Young adult (18 - 40 years)
1 - 10 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
There are no material preservation details for this sample set |
Male
Adult (> 40 years)
1 - 10 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
There are no material preservation details for this sample set |
Female
Young adult (18 - 40 years)
1 - 10 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
There are no material preservation details for this sample set |
Female
Adult (> 40 years)
1 - 10 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
There are no material preservation details for this sample set |