Mesothelioma (malignant, clinical disorder) (disorder)
Mesobank
Year Started: 2014
REC approved, Research Tissue Bank providing fresh frozen samples of tumour, blood, pleural fluid and DNA.
- Access:
- Open to applicants
- Type:
- Disease specific
- Status:
- In progress
- Consent restrictions:
- Other animal work restriction, Xenograft restriction
Associated Data Type | Procurement Timeframe |
---|---|
Clinical records | Immediate |
Freezer temperature logs | Immediate |
National registries | Immediate |
Pathology records | Immediate |
Physiological/biochemical measurements | Immediate |
Quality indicators | Immediate |
Treatment records | Immediate |
Donor Ethnicity | Immediate |
Male
Adult (> 40 years)
101 - 500 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Tissue specimen | -60°C to -85°C | Affected | 75% -99% |
Female
Adult (> 40 years)
11 - 100 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Tissue specimen | -60°C to -85°C | Affected | 51 - 75% |
Male
Adult (> 40 years)
11 - 100 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Tissue specimen | -60°C to -85°C | Non-affected | 51 - 75% |
Female
Adult (> 40 years)
1 - 10 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Tissue specimen | -60°C to -85°C | Non-affected | 100% |
Mesothelioma (malignant, clinical disorder) (disorder)
TMA
Year Started: 2014
A tissue microarray (TMA) containing tumour cores from 800 patients is available. This has been constructed by the Cancer Research UK Cambridge TMA facility using paraffin-embedded blocks from cases that have been diagnosed in hospitals across the UK. A minimum of four cores is taken from each block to allow for tumour heterogeneity. The TMA has been constructed in modular form to facilitate test and validation cohorts. Cut slides are dipped in wax.
- Access:
- Open to applicants
- Type:
- Disease specific
- Status:
- Completed
- Consent restrictions:
- Other animal work restriction, Xenograft restriction
Associated Data Type | Procurement Timeframe |
---|---|
Clinical records | 0 - 3 months |
Imaging data | 0 - 3 months |
National registries | 0 - 3 months |
Pathology records | 0 - 3 months |
Quality indicators | 0 - 3 months |
Treatment records | 0 - 3 months |
Donor Ethnicity | 0 - 3 months |
Female
Adult (> 40 years)
101 - 500 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Tissue specimen | RT | Affected | 100% |
Male
Adult (> 40 years)
501 - 1000 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Tissue specimen | RT | Affected | 100% |