Fit and well (finding)

TwinsUK

Year Started: 2004

From ~14,500 registered twins 9,900 unique individuals have visited to collect biological samples. Some individuals will have multiple samples collected at different time points. Note that numbers provided should be used as guidance only since the collection is ongoing.



Access:
Open to applicants
Type:
Twin-study
Status:
In progress
Consent restrictions:
Other animal work restriction, Xenograft restriction


Associated Data Type Procurement Timeframe
Biomarker datasets 0 - 3 months
Clinical records 0 - 3 months
Followup records 0 - 3 months
Genomic datasets 0 - 3 months
Imaging data 0 - 3 months
Physiological/biochemical measurements 0 - 3 months
Survey data 0 - 3 months
Treatment records 0 - 3 months
Psychological data 0 - 3 months
Donor Ethnicity 0 - 3 months


Female

Adult (> 40 years)

5001 - 10000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
Immortalized cell lines Liquid nitrogen liquid phase N/A Not applicable 51 - 75%
DNA -18°C to -35°C N/A Not applicable 100%
Peripheral blood mononuclear cells (PBMC) Liquid nitrogen liquid phase N/A Not applicable 26 - 50%
Plasma -60°C to -85°C N/A Not applicable 75% -99%
Saliva -60°C to -85°C N/A Not applicable 26 - 50%
Serum -60°C to -85°C N/A Not applicable 75% -99%
Urine -60°C to -85°C N/A Not applicable 75% -99%


Male

Adult (> 40 years)

501 - 1000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -18°C to -35°C N/A Not applicable 100%
Peripheral blood mononuclear cells (PBMC) Liquid nitrogen liquid phase N/A Not applicable 26 - 50%
Plasma -60°C to -85°C N/A Not applicable 75% -99%
Saliva -60°C to -85°C N/A Not applicable 51 - 75%
Serum -60°C to -85°C N/A Not applicable 75% -99%
Urine -60°C to -85°C N/A Not applicable 75% -99%
Immortalized cell lines Liquid nitrogen liquid phase N/A Not applicable 51 - 75%

Fit and well (finding)

GrandMuTHER

Year Started: 2011



Access:
Open to applicants
Type:
Twin-study
Status:
In progress
Consent restrictions:
Other animal work restriction, Xenograft restriction


Associated Data Type Procurement Timeframe
Biomarker datasets 0 - 3 months
Clinical records 0 - 3 months
Followup records 0 - 3 months
Genomic datasets 0 - 3 months
Imaging data 0 - 3 months
Physiological/biochemical measurements 0 - 3 months
Survey data 0 - 3 months
Psychological data 0 - 3 months
Donor Ethnicity 0 - 3 months


Female

Adult (> 40 years)

501 - 1000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -18°C to -35°C N/A Not applicable 100%
Plasma -60°C to -85°C N/A Not applicable 26 - 50%
Saliva -60°C to -85°C N/A Not applicable 26 - 50%
Serum -60°C to -85°C N/A Not applicable 26 - 50%
Tissue specimen Surgical procedure (procedure) -60°C to -85°C N/A Not applicable 0 - 10%
Tissue specimen Surgical procedure (procedure) Liquid nitrogen liquid phase N/A Not applicable 26 - 50%
Urine -60°C to -85°C N/A Not applicable 26 - 50%

Fit and well (finding)

Flora Study

Year Started: 2012



Access:
Open to applicants
Type:
Twin-study
Status:
In progress
Consent restrictions:
Other animal work restriction, Xenograft restriction


Associated Data Type Procurement Timeframe
Biomarker datasets 0 - 3 months
Clinical records 0 - 3 months
Followup records 0 - 3 months
Genomic datasets 0 - 3 months
Imaging data 0 - 3 months
Physiological/biochemical measurements 0 - 3 months
Survey data 0 - 3 months
Psychological data 0 - 3 months
Donor Ethnicity 0 - 3 months


Female

Adult (> 40 years)

3001 - 5000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -18°C to -35°C N/A Not applicable 26 - 50%
Faeces -60°C to -85°C N/A Not applicable 75% -99%


Male

Adult (> 40 years)

501 - 1000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -18°C to -35°C N/A Not applicable 51 - 75%
Faeces -60°C to -85°C N/A Not applicable 75% -99%

Fit and well (finding)

PREDICT

Year Started: 2018



Access:
Open to applicants
Type:
Twin-study
Status:
In progress
Consent restrictions:
Other animal work restriction, Xenograft restriction


Associated Data Type Procurement Timeframe
Biomarker datasets 0 - 3 months
Clinical records 0 - 3 months
Followup records 0 - 3 months
Genomic datasets 0 - 3 months
Imaging data 0 - 3 months
Physiological/biochemical measurements 0 - 3 months
Survey data 0 - 3 months
Psychological data 0 - 3 months
Donor Ethnicity 0 - 3 months


Female

Adult (> 40 years)

501 - 1000 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -18°C to -35°C N/A Not applicable 26 - 50%
Faeces -60°C to -85°C N/A Not applicable 100%
Plasma -60°C to -85°C N/A Not applicable 100%
Saliva -60°C to -85°C N/A Not applicable 100%
Serum -60°C to -85°C N/A Not applicable 100%
Urine -60°C to -85°C N/A Not applicable 75% -99%
Dried whole blood (e.g. Guthrie cards) DWB -18°C to -35°C N/A Not applicable 75% -99%


Male

Adult (> 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -18°C to -35°C N/A Not applicable 26 - 50%
Faeces -60°C to -85°C N/A Not applicable 100%
Plasma -60°C to -85°C N/A Not applicable 75% -99%
Saliva -60°C to -85°C N/A Not applicable 100%
Serum -60°C to -85°C N/A Not applicable 100%
Urine -60°C to -85°C N/A Not applicable 100%
Dried whole blood (e.g. Guthrie cards) DWB -18°C to -35°C N/A Not applicable 75% -99%

Fit and well (finding)

Keeping Together

Year Started: 2018



Access:
Open to applicants
Type:
Twin-study
Status:
In progress
Consent restrictions:
Other animal work restriction, Xenograft restriction


Associated Data Type Procurement Timeframe
Biomarker datasets 0 - 3 months
Clinical records 0 - 3 months
Followup records 0 - 3 months
Genomic datasets 0 - 3 months
Imaging data 0 - 3 months
Physiological/biochemical measurements 0 - 3 months
Survey data 0 - 3 months
Psychological data 0 - 3 months
Donor Ethnicity 0 - 3 months


Female

Adult (> 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -18°C to -35°C N/A Not applicable 75% -99%
Faeces -60°C to -85°C N/A Not applicable 75% -99%
Plasma -60°C to -85°C N/A Not applicable 75% -99%
Saliva -60°C to -85°C N/A Not applicable 75% -99%
Urine -60°C to -85°C N/A Not applicable 75% -99%


Male

Adult (> 40 years)

11 - 100 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Macroscopic Assessment % of Sample Set
DNA -18°C to -35°C N/A Not applicable 75% -99%
Faeces -60°C to -85°C N/A Not applicable 26 - 50%
Plasma -60°C to -85°C N/A Not applicable 75% -99%
Saliva -60°C to -85°C N/A Not applicable 26 - 50%
Urine -60°C to -85°C N/A Not applicable 51 - 75%