Malignant tumor of kidney (disorder)
Renal Cancer Biomarkers (NIHR Biomarker Programme)
Year Started: 2011
706 patients recruited across 11 UK centres: 494 cross sectional cohort with single time point and 212 with multiple samples as a longitudinal cohort. 511 tissue samples: 375 FFPE only, 18 frozen only and 118 both. For each patient at each timepoint, multiple aliquots of EDTA plasma, serum, and urine are stored frozen at -80ºC together with a buffy coat sample. Digital images are available for some of the tissue samples. Clinical data including long-term follow-up is held by Leeds Clinical Trials Research Unit.
- Access:
- Open only through collaboration
- Type:
- Disease specific
- Status:
- Completed
- Consent restrictions:
- No restrictions
Associated Data Type | Procurement Timeframe |
---|---|
Biomarker datasets | 0 - 3 months |
Clinical records | 0 - 3 months |
Followup records | 0 - 3 months |
Freezer temperature logs | 0 - 3 months |
Genomic datasets | 0 - 3 months |
Imaging data | 0 - 3 months |
Pathology records | 0 - 3 months |
Physiological/biochemical measurements | 0 - 3 months |
Treatment records | 0 - 3 months |
Unknown
Adult (> 40 years)
501 - 1000 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Plasma | -60°C to -85°C | N/A | Not applicable | 100% | |
Serum | -60°C to -85°C | N/A | Not applicable | 100% | |
Tissue specimen | Surgical procedure (procedure) | Liquid nitrogen liquid phase | N/A | Not applicable | 11 - 25% |
Tissue specimen | Surgical procedure (procedure) | RT | Paraffin | Not applicable | 51 - 75% |
Urine | -60°C to -85°C | N/A | Not applicable | 100% |