Malignant tumor of kidney (disorder)
Renal Cancer Biomarkers (NIHR Biomarker Programme)
Year Started: 2011
706 patients recruited across 11 UK centres: 494 cross sectional cohort with single time point and 212 with multiple samples as a longitudinal cohort. 511 tissue samples: 375 FFPE only, 18 frozen only and 118 both. For each patient at each timepoint, multiple aliquots of EDTA plasma, serum, and urine are stored frozen at -80ºC together with a buffy coat sample. Digital images are available for some of the tissue samples. Clinical data including long-term follow-up is held by Leeds Clinical Trials Research Unit.
- Access:
- Open only through collaboration
- Type:
- Disease specific
- Status:
- Completed
- Consent restrictions:
- No restrictions
Associated Data Type | Procurement Timeframe |
---|---|
Biomarker datasets | 0 - 3 months |
Clinical records | 0 - 3 months |
Followup records | 0 - 3 months |
Freezer temperature logs | 0 - 3 months |
Genomic datasets | 0 - 3 months |
Imaging data | 0 - 3 months |
Pathology records | 0 - 3 months |
Physiological/biochemical measurements | 0 - 3 months |
Treatment records | 0 - 3 months |
Unknown
Adult (> 40 years)
501 - 1000 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Plasma | -60°C to -85°C | N/A | Not applicable | 100% | |
Serum | -60°C to -85°C | N/A | Not applicable | 100% | |
Tissue specimen | Surgical procedure (procedure) | Liquid nitrogen liquid phase | N/A | Not applicable | 11 - 25% |
Tissue specimen | Surgical procedure (procedure) | RT | Paraffin | Not applicable | 51 - 75% |
Urine | -60°C to -85°C | N/A | Not applicable | 100% |
Fit and well (finding)
Healthy controls in NIHR Biomarker Programme
Year Started: 2011
Cross-sectional EDTA plasma, serum and urine samples have been collected from 149 healthy controls across multiple UK centres together with relevant demographic data. Samples have been collected using standardised SOPs and aliquots are stored in multiple aliquots at -80ºC. Demographic data is held by Leeds Clinical Trials Research Unit
- Access:
- Open only through collaboration
- Type:
- Cross-sectional
- Status:
- Completed
- Consent restrictions:
- No restrictions
Associated Data Type | Procurement Timeframe |
---|---|
Freezer temperature logs | 0 - 3 months |
Unknown
Adult (> 40 years)
101 - 500 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Plasma | -60°C to -85°C | N/A | Not applicable | 100% | |
Serum | -60°C to -85°C | N/A | Not applicable | 100% | |
Urine | -60°C to -85°C | N/A | Not applicable | 100% |
Cirrhosis of liver (disorder)
ELUCIDATE Liver Cirrhosis Study
Year Started: 2011
847 patients with liver disease across multiple UK centres have consented and provided a single serum sample. Serum samples collected using standardised SOPs are stored in multiple aliquots at -80ºC. Clinical data is held by Leeds Clinical Trials Research Unit.
- Access:
- Open only through collaboration
- Type:
- Cross-sectional
- Status:
- Completed
- Consent restrictions:
- No restrictions
Associated Data Type | Procurement Timeframe |
---|---|
Biomarker datasets | 0 - 3 months |
Clinical records | 0 - 3 months |
Followup records | 0 - 3 months |
Freezer temperature logs | 0 - 3 months |
Physiological/biochemical measurements | 0 - 3 months |
Treatment records | 0 - 3 months |
Unknown
Adult (> 40 years)
501 - 1000 donors
Material Type | Extraction Procedure | Storage Temperature | Preservation Type | Macroscopic Assessment | % of Sample Set |
---|---|---|---|---|---|
Serum | -60°C to -85°C | N/A | Not applicable | 100% |