Centre for Longitudinal Studies (CLS)

All samples currently in the tissue bank were collected from three unique and powerful longitudinal cohort studies run by the Centre for Longitudinal Studies at the UCL Institute of Education: the 1958 birth cohort (also known as the National Child Development Study), the 1970 British Cohort Study and the Millenium Cohort Study. The 1958 birth cohort study (NCDS) recruited over 17,000 individuals who were born in one week in 1958. Biological samples were collected from approximately 8000 study participants as part of a biomedical survey in 2002-2003. Additional blood samples from approximately 7000 study participants are being collected in the 2019-2021 biomedical sweep and will be added to the collection. The 1970 British Cohort Study (BCS) follows the lives of those born in one week in 1970. The 2016-2018 Biomedical Survey for BCS70 collected whole blood samples from approximately 6000 cohort members. The most recent of Britain’s renowned national longitudinal cohort studies, the Millenium Cohort Study (MCS), follows the lives of over 19,000 children in the UK born in 2000/1. At age 14 (MCS6) saliva was collected from approximately 9300 cohort members and 14,000 natural parents (where present in the home) to create a DNA bank. The subjects in these studies have been well characterised (phenotyped) for a variety of quantitative complex traits and been assessed for a variety of sociodemographic, socioeconomic and lifestyle variables. The resource is widely used for research in genetic and genomic epidemiology, in particular as a platform for genetic association studies. Data has been collected from the NCDS, BCS, Next Steps and MCS birth cohort participants via interviews, questionnaires and home visits since their birth in 1958, 1970, 1989/1990 and 2000/2001 respectively. The tissue bank however only holds a limited amount of information pertinent to managing the samples and the genotyping and analytical data generated from the samples. The tissue bank holds no identifying information, all samples and data held by the bank are linked by a participant id number. The resources in the tissue bank are available to bona fide research scientists. Access to samples will be subject to successful application to METADAC (https://www.metadac.ac.uk/).

Services

  • Ability to recontact
  • Cell culture
  • Nucleic acid extraction

Existing samples:

  • Fit and well

Contact Information

Email:
clsfeedback@ucl.ac.uk
Telephone:
020 7612 6875
Address:

20 Bedford Way
London
London
WC1H 0AL
UK

Annual Statistics

Year Access Requests Received Access Requests Approved
Internal External Commercial Internal External Commercial
2015 N/A N/A N/A N/A N/A N/A
2016 N/A N/A N/A N/A N/A N/A
2017 N/A N/A N/A N/A N/A N/A
2018 N/A N/A N/A N/A N/A N/A
2019 N/A N/A N/A N/A N/A N/A
2020 N/A N/A N/A N/A N/A N/A