NIHR BioResource

NIHR BioResource is a unique and powerful resource for studying disease mechanisms and for investigating the links between genes, the environment, health and disease; enabling scientific discoveries as well as facilitating translational medicine for the benefit of patients. Our mission is to facilitate human health research and its transformation into medical practice. We have over 150,000 consented volunteers, from the general population and patients with common and rare diseases. BioResource volunteers are willing to be recalled according to their genotype and/or phenotype and to participate in academic and industry-led experimental medicine and clinical research studies. We aim to have 300,000 volunteers by the end of March 2022. Participants who join the NIHR BioResource donate their DNA via a blood or saliva sample which is used together with other information (e.g. gender, ethnicity, health records, genomics), to match them to specific research studies. Genotyping information via high density array is available for most of the BioResource panel, and many of those with rare diseases have whole genome sequencing data available. Where blood samples were taken, plasma, sera and wholeblood samples are banked and - along with underlying data - these samples may be requested through our approvals process, see https://bioresource.nihr.ac.uk/researchers/researchers/application-process/ To date around 1 in 4 requests we receive are for samples and/or data only. As well as healthy volunteers, primarily blood donors, the NIHR BioResource has enrolled over 10,000 patients with Rare Diseases, and has large cohorts of patients with anxiety and depression, and Inflammatory Bowel Disease. New patient cohorts are continuously being added. Industry partners may encounter a cost to access BioResource volunteers. A detailed cost for Industry-led studies through commercial agreements can be found at: https://bioresource.nihr.ac.uk/industry/industry-home/

Services

  • Ability to recontact
  • Data analytics

Existing samples:

  • Depressive disorder (disorder)
  • Fit and well
  • Inflammatory bowel disease (disorder)

Bespoke collection capabilities:

  • Attention deficit hyperactivity disorder (disorder)
  • Depressive disorder (disorder)
  • Diabetes mellitus type 1
  • Diabetes mellitus type 2
  • Fibromyalgia (disorder)
  • Fit and well
  • Hyperlipidemia (disorder)
  • Hypertensive disorder, systemic arterial (disorder)
  • Hypothyroidism (disorder)
  • Inflammatory bowel disease (disorder)
  • Ischemic heart disease (disorder)
  • Migraine (disorder)
  • Multiple sclerosis (disorder)
  • Parkinson's disease (disorder)

Contact Information

Email:
nbr@bioresource.nihr.ac.uk
Telephone:
0800 090 2233
Address:

NIHR BioResource, Box 299
University of Cambridge and Cambridge University Hospitals NHS Foundation Trust
Cambridge Biomedical Campus
Hills Road
Cambridge
Cambridgeshire
CB2 0QQ
UK

Annual Statistics

Year Access Requests Received Access Requests Approved
Internal External Commercial Internal External Commercial
2015 N/A N/A N/A N/A N/A N/A
2016 N/A N/A N/A N/A N/A N/A
2017 N/A N/A N/A N/A N/A N/A
2018 0 7 0 0 7 0
2019 0 3 0 0 3 0
2020 0 1 0 0 1 0